Peptide Agent Docs

Everything you need to know about using the AI-powered peptide discovery platform.

Overview

Peptide Agent is an AI-powered tool for early-stage peptide drug discovery. You describe a health condition or biological target in plain English, and the system generates a synthetic peptide candidate with predicted properties including binding mechanism, stability, and toxicity profile.

The platform is designed for researchers, biotech founders, and curious minds who want a fast, explainable starting point for peptide hypothesis generation. All results are AI-predicted and require laboratory validation before any clinical use.

Research use only. Results are AI-generated predictions and are not intended as medical advice or clinical guidance.

Quick Start

  1. Enter a condition or target

    Type a disease, condition, or biological target into the search field. Examples: acne treatment, anti-inflammatory peptide, wound healing, GLP-1 receptor agonist.

  2. Click Discover Peptide

    The AI analyzes your query, searches known peptide data, and generates a candidate sequence with supporting analysis. This typically takes 3–6 seconds.

  3. Review the output

    You'll receive a peptide sequence, confidence score, mechanism tag, stability and toxicity predictions, and a similarity table comparing against known peptides from UniProt.

  4. Save and share

    Click Save Result to store the result and generate a permanent shareable link (e.g. app.peptideagent.xyz/result/[id]).

Rate Limits

Each IP address is limited to 10 requests per day. This resets at midnight UTC. Your remaining requests are shown in the navigation bar after your first query.

TierRequests/dayCost
Free10Free
Research (coming soon)UnlimitedContact us

Need higher limits? Email support@peptideagent.xyz.

Sequence Generation

Sequences are generated by GPT-4o with a domain-specific system prompt trained on peptide biology principles. The model outputs single-letter amino acid codes using the standard 20 canonical amino acids:

A C D E F G H I K L M N P Q R S T V W Y

Generated sequences are typically 6–20 amino acids in length, optimized for the described target based on known structural motifs (amphipathicity, charge distribution, hydrophobicity patterns).

Output Fields

FieldDescription
sequenceThe suggested amino acid sequence in single-letter code
confidenceAI confidence score (60–95%) based on query clarity and known data
explanationScientific rationale for the sequence design
mechanismPredicted biological mechanism tag
stabilityPredicted stability: High / Medium / Low
halfLifeEstimated half-life in biological media
toxicityPredicted toxicity flag (non-toxic / low / moderate)
molecularWeightApproximate molecular weight in kDa
similarityTop 3 similar known peptides from UniProt

Similarity Search

After generating a sequence, the platform queries the UniProt REST API to find structurally or functionally similar known peptides. This provides biological context and validation anchors for the generated candidate.

If UniProt returns no close matches, a curated fallback set of well-known reference peptides is used based on the predicted mechanism.

Sharing Results

Every saved result gets a permanent URL:

app.peptideagent.xyz/result/[uuid]

Anyone with the link can view the full result — sequence, explanation, metrics, and similarity table. Results are stored in our database and do not expire.

Supported Conditions

The system accepts any plain-English description of a biological target or condition. Pre-built examples include:

AcneAnti-agingWound HealingMuscle RecoveryAnti-inflammatoryAntimicrobialCognitive FunctionImmune ModulationDiabetesHair GrowthGut HealthPain Relief

You can also enter custom targets like receptor names, pathogen names, or specific biological pathways.

Mechanism Tags

TagDescription
AntimicrobialDisrupts bacterial or fungal cell membranes
Anti-inflammatoryModulates inflammatory cytokine pathways
HormonalMimics or modulates hormonal signaling (e.g. GLP-1, insulin)
NeuropeptideActs on neural signaling pathways
AntifungalTargets fungal cell wall or membrane
AntiviralInhibits viral entry or replication
Cell-signalingModulates intracellular signaling cascades
Wound-healingPromotes tissue repair and regeneration

Disclaimer

Important: All sequences and predictions generated by Peptide Agent are AI-generated outputs for research exploration only. They have not been experimentally validated. Do not use these results for clinical, diagnostic, or therapeutic purposes without proper laboratory validation and regulatory review. Peptide Agent is not responsible for any decisions made based on these predictions.

For questions, contact support@peptideagent.xyz.